Of the 57 eligible RCTs ( n = 4295), 51 RCTs were included in quantitative analyses
Previous meta-analyses of psychotherapies for children and adolescents with post-traumatic stress disorder (PTSD) did not investigate whether treatment efficacy is diminished when patients report multiple (versus single) traumas.
We systematically searched PsycInfo, MEDLINE, Web of Science and PTSDpubs on and included randomised controlled trials (RCTs) meeting the following criteria: (a) random allocation; (b) all participants presented with partial or full PTSD; (c) PTSD is the priple mean age
Relative to passive control conditions, interventions were found effective for single-trauma-related PTSD (Hedges’ g = 1.09; 95% CI 0.70–1.48; k = 8 trials) and multiple-trauma-related PTSD ( g = 1.11; 95% CI 0.74–1.47; k = 12). Psychotherapies were also more effective than active control conditions in reducing multiple-trauma-related PTSDparison with active control conditions regarding single-event PTSD was not possible owing to scarcity ( k = 1) of available trials.